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        Calcipotriol

        IUPAC name:

        (1R,3S,5E)-5-{2-[(1R,3aS,4Z,7aR)-1-[(2R,3E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohyytyexane-1,3-diol

        Trade name:Daivobex, Dovobex, Sorilux

        CAS No.:112965-21-6

        Molecular Formula: C27H40O3

        Molar mass:412.605

        Pharmacology action: This product is similar to vitamin D analogues, the pharmacodynamic properties and vitamin D3 active metabolite of Calcitriol. In several in vitro models of this product and Calcitriol significantly inhibit cell proliferation and stimulate cell differentiation, such as both reduce the number of cells, total DNA content and radiation labeled thymidine incorporation into DNA, increase human keratinocytes and enhance the activity of the protein cross-linking enzyme, inhibit the proliferation and differentiation of epidermal cells.

        On a:Calcitriol

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